Adhesive Disease and Your OB/GYN Practice

Adhesions are more common than you might think1-4

As you know, there are many complications that frequently occur following a C-section. According to one study, common complications of primary C-sections include fever, uterine laceration, blood loss (≥1000 mL), and urinary tract infection.5

Adhesions may form after 46% to 65% of primary C-sections1-4

Adhesions are an often-overlooked and potentially harmful complication.

Incidents of adhesion following primary C-sections

The impact of adhesions on you and your patients

Adhesions can cause:

  • Increased risk of infertility6
  • Prolonged overall OR time7
  • Delayed deliveries1
  • Chronic pelvic pain8
  • Small bowel obstruction9

With every subsequent C-section, the incidence and severity of adhesions can increase.1,10

Indication
Seprafilm® Adhesion Barrier is indicated for the reduction of post-surgical adhesions in patients undergoing abdominal or pelvic laparotomy.

Important Safety Information
Seprafilm should not be wrapped around an intestinal anastomosis as such usage may result in increased anastomotic leak related events, such as abscess or peritonitis. The safety and effectiveness of Seprafilm has not been established in combination with other adhesion prevention products and/or in surgical procedures not within the abdominopelvic cavity. The safety and effectiveness of Seprafilm has also not been evaluated in cases of pregnancy, malignancy, or frank infection. The type and frequency of adverse events reported are consistent with events typically seen following abdominopelvic surgery when used as directed.

Please see full prescribing information.

Explore the latest insights in adhesive disease.

PDF Download Download a complimentary copy of "Preventing Adhesions in ObGyn Surgery," by Dr Victor Hugo González-Quintero, for a review of adjunctive methods to help prevent postoperative adhesion formation.

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What is SEPRAFILM®?

Discover the science behind SEPRAFILM Adhesion Barrier.

The science

References:  1. Morales KJ, Gordon MC, Bates GW Jr. Postcesarean delivery adhesions associated with delayed delivery of infant. Am J Obstet Gynecol. 2007;196(online):461.e1-461.e6.  2. Fushiki H, Ikoma T, Kobayashi H, Yoshimoto H. Efficacy of Seprafilm as an adhesion prevention barrier in cesarean sections. Obstet Gynecol Treatment. 2005;91:557-561.  3. Hamel K. Incidence of adhesions at repeat cesarean delivery. Am J Obstet Gynecol. 2007;196(online):e31-e32.  4. Lyell DJ, Caughey AB, Hu E, Daniels K. Peritoneal closure at primary cesarean delivery and adhesions. Obstet Gynecol. 2005;106:275-280.  5. van Ham MAPC, van Dongen PWJ, Mulder J. Maternal consequences of caesarean section: a retrospective study of intra-operative and postoperative maternal complications of caesarean section during a 10-year period. Eur J Obstet Gynecol Reprod Biol. 1997;74:1-6.  6. DeWilde RL, Trew G; for Expert Adhesions Working Party of the European Society of Gynaecological Endoscopy (ESGE). Postoperative abdominal adhesions and their prevention in gynaecological surgery. Expert consensus position. Gynecol Surg. 2007;4:161-168.  7. Tulandi T, Agdi M, Zarei A, Miner L, Sikirica V. Adhesion development and morbidity after repeat cesarean delivery. Am J Obstet Gynecol. 2009;201(online):56.e1-56.e6.  8. Keltz MD, Gera PS, Olive DL. Prospective randomized trial of right-sided paracolic adhesiolysis for chronic pelvic pain. J Soc Laparoendosc Surg. 2006;10:443-446.  9. Ellis H, Moran BJ, Thompson JN, et al. Adhesion-related hospital readmissions after abdominal and pelvic surgery: a retrospective cohort study. Lancet. 1999;353:1476-1480.  10. Makoha FW, Felimban HM, Fathuddien MA, Roomi F, Ghabra T. Multiple cesarean section morbidity. Int J Gynecol Obstet. 2004;87:227-232.