How are adhesions impacting your practice?

Adhesions may form after 46% to 65% of primary C-Sections.1,3-5

Adhesive disease

What is Seprafilm?

Seprafilm is a temporary, bioresorbable adhesion barrier proven to reduce the incidence, extent, and severity of adhesions in patients undergoing abdominal or pelvic laparotomy.2,6

 

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Seprafilm in hysterectomy and myomectomy Reduce adhesions in other abdominopelvic surgeries with Seprafilm.

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Introducing Seprafilm 4-Section

Packaged to improve exchange in the OR, Seprafilm 4-Section—four 3" x 2.5" precut sheets—provides the same overall coverage as the original 5" x 6" Seprafilm Adhesion Barrier.

 

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Indication
Seprafilm® Adhesion Barrier is indicated for the reduction of post-surgical adhesions in patients undergoing abdominal or pelvic laparotomy.

Important Safety Information
Seprafilm should not be wrapped around an intestinal anastomosis as such usage may result in increased anastomotic leak related events, such as abscess or peritonitis. The safety and effectiveness of Seprafilm has not been established in combination with other adhesion prevention products and/or in surgical procedures not within the abdominopelvic cavity. The safety and effectiveness of Seprafilm has also not been evaluated in cases of pregnancy, malignancy, or frank infection. The type and frequency of adverse events reported are consistent with events typically seen following abdominopelvic surgery when used as directed.

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References:   1. Fushiki H, Ikoma T, Kobayashi H, Yoshimoto H. Efficacy of Seprafilm as an adhesion prevention barrier in cesarean sections. Obstet Gynecol Treatment. 2005;91:557-561.  2. Diamond MP. Reduction of adhesions after uterine myomectomy by Seprafilm membrane (HAL-F): a blinded, prospective, randomized, multicenter clinical study. Fertil Sterility. 1996;66:904-910.  3. Morales KJ, Gordon MC, Bates GW Jr. Postcesarean delivery adhesions associated with delayed delivery of infant. Am J Obstet Gynecol. 2007;196(online):461.e1-461.e6.  4. Hamel K. Incidence of adhesions at repeat cesarean delivery. Am J Obstet Gynecol. 2007;196(online):e31-e32.  5.  Lyell DJ, Caughey AB, Hu E, Daniels K. Peritoneal closure at primary cesarean delivery and adhesions. Obstet Gynecol. 2005;106:275-280.  6. Becker JM, Dayton MT, Fazio VW, et al. Prevention of postoperative abdominal adhesions by a sodium hyaluronate-based bioresorbable membrane: a prospective, randomized, double-blind multicenter study. J Am Coll Surg. 1996;183:297-306.